Dr Rick Dijkhuizen


Rick Dijkhuizen is a neurobiologist who received his Ph.D. at Utrecht University in 1998 (thesis title: 'Magnetic Resonance Imaging and Spectroscopy in Experimental Cerebral Ischemia'). From 1999 until 2002 he worked at the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Massachusetts Institute of Technology/Harvard Medical School (Charlestown/Boston, MA, USA), first as Postdoctoral Fellow and later as Instructor. There his research focused on elucidating spontaneous and therapy-induced recovery after cerebrovascular injury (e.g., stroke) with different MRI techniques in patients and experimental models.
In 2002, he became head of the Biomedical MR Imaging and Spectroscopy Group at the University Medical Center Utrecht. He holds a position as Associate Professor and is responsible for daily management of the preclinical MRI facility (equipped with 4.7 T and 9.4 T MR systems), coordination of internal and external research projects, and supervision of postdoctoral researchers and Ph.D. students.

His current research interests include multiparametric imaging of brain structure and function in health and disease, with a particular focus on i) development of tools for improved diagnosis of brain pathophysiology, ii) characterization of neural network (re)organization, and iii) monitoring of neuroprotective and -restorative therapies. He collaborates with various national and international academic institutions, is workpackage leader in two EU-FP7 research programs (EUSTROKE and TACTICS), and has held different (inter)national committee assignments. He is an active member of the EU-funded European Stroke Network, and serves on the Board of Directors of the International Society for Cerebral Blood Flow and Metabolism, and the Editorial Boards of the Journal of Cerebral Blood Flow and Metabolism and Translational Stroke Research.
Rick Dijkhuizen has received funding for his research from the American Heart Association (Postdoctoral Fellowship Award), the Commission of the European Communities (FP7), the National Institutes of Health (R01), the Netherlands Epilepsy Foundation, the Netherlands Heart Foundation, the Netherlands Organization for Scientific Research (Talent Fellowship Award, VIDI Award, NWO-Groot, TOP, VICI Award), the Qatar National Research Fund (National Priorities Research Program), the Royal Netherlands Academy of Arts and Sciences (Fellowship Award), and Utrecht University (High Potential Award).

Currently, Rick Dijkhuizen is a Visiting Associate Professor at the Department of Radiology at Stanford University School of Medicine, where he is involved in the Molecular Imaging Program at Stanford.

Key publications:

  • Experimental focal neocortical epilepsy is associated with reduced white matter volume growth: results from multiparametric MRI analysis. Otte WM, van Meer MP, van der Marel K, Zwartbol R, Viergever MA, Braun KP, Dijkhuizen RM. Brain Struct Funct. 2013 Sep 8. [Epub ahead of print]
  • Imaging neuronal loss and recovery in compromised but viable brain tissue. Dijkhuizen RM. Brain. 2013;136:1689-91.
  • MRI of ICAM-1 upregulation after stroke: the importance of choosing the appropriate target-specific particulate contrast agent. Deddens LH, van Tilborg GA, van der Toorn A, van der Marel K, Paulis LE, van Bloois L, Storm G, Strijkers GJ, Mulder WJ, de Vries HE, Dijkhuizen RM. Mol Imaging Biol. 2013;15:411-22.
  • Early identification of potentially salvageable tissue with MRI-based predictive algorithms after experimental ischemic stroke. Bouts MJ, Tiebosch IA, van der Toorn A, Viergever MA, Wu O, Dijkhuizen RM. J Cereb Blood Flow Metab. 2013;33:1075-82.
  • Extent of bilateral neuronal network reorganization and functional recovery in relation to stroke severity. van Meer MP, Otte WM, van der Marel K, Nijboer CH, Kavelaars A, Berkelbach van der Sprenkel JW, Viergever MA, Dijkhuizen RM. J Neurosci. 2012;32:4495-507.
  • In vivo imaging of neurovascular remodeling after stroke. Yanev P, Dijkhuizen RM. Stroke. 2012;43:3436-41.
  • Contribution of the left and right inferior frontal gyrus in recovery from aphasia. A functional MRI study in stroke patients with preserved hemodynamic responsiveness. van Oers CA, Vink M, van Zandvoort MJ, van der Worp HB, de Haan EH, Kappelle LJ, Ramsey NF, Dijkhuizen RM. Neuroimage. 2010;49:885-93.
  • Structural and functional plasticity in the somatosensory cortex of chronic stroke patients. Schaechter JD, Moore CI, Connell BD, Rosen BR, Dijkhuizen RM. Brain. 2006;129:2722-33.
  • Magnetic resonance imaging in experimental models of brain disorders. Dijkhuizen RM, Nicolay K. J Cereb Blood Flow Metab. 2003;23:1383-402. Review.
  • Functional magnetic resonance imaging of reorganization in rat brain after stroke. Dijkhuizen RM, Ren J, Mandeville JB, Wu O, Ozdag FM, Moskowitz MA, Rosen BR, Finklestein SP. Proc Natl Acad Sci U S A. 2001;98:12766-71.

 
 
 Image Sciences Institute
 University Medical Center Utrecht
 Bolognalaan 50
 3584 CJ Utrecht
 The Netherlands
publications of  R.M. Dijkhuizen
email:rick@invivonmr.uu.nl
office: GDL/Bolognalaan 50
phone: +31 30 253 5569
secretary: +31 88 75 57772
fax: +31 30 253 5561