Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart
Tseng, Cheyenne C S, Wenker, Steven, Bakker, Maarten H, Kraaijeveld, Adriaan O, Dankers, Patricia Y W, Seevinck, Peter R, Smink, Jouke, Kimmel, Scott, van Slochteren, Frebus J, Chamuleau, Steven A J
DOI: https://doi.org/10.4244/EIJ-D-17-01081
EuroIntervention 15 (4), p. e336-e339
Abstract
The MIGRATE (MrI Guided RegenerAtive ThErapy) consortium is a combined scientific and industrial effort to establish an MRIguided intramyocardial injection platform. By collaborating within the MIGRATE consortium we were able to combine state-of-theart interventional imaging hardware, software, MRI-compatible catheters, and biomaterials. In this pilot study, we demonstrated the feasibility of intramyocardial injections of an MRI-visible biomaterial by interventional MRI using a combination of active tracking and passive visualisation.