Peter Seevinck graduated Biomedical Engineering at the Eindhoven University of Technology in 2005. In 2009, he received his PhD in Medical Imaging at Utrecht University after defending his thesis entitled “Multimodal imaging of holmium-loaded microspheres for internal radiation therapy”.
Currently Peter is appointed Associate Professor (UHD) at the Image Sciences Institute in the Imaging Division of UMC Utrecht. He acts as a coordinator and lecturer in several courses in the field of MRI. His research is focusing on the development and clinical introduction of novel MR imaging methods and advanced machine learning algorithms for minimally invasive and safe personalized image-guided diagnosis and therapy. Examples of these novel approaches include MRI-guided device visualization for cardiac stem cell therapy and brachytherapy, MRI-only radiotherapy treatment planning for more efficient and shorter treatment workup and MRI-based bone imaging (BoneMRI), reducing radiation burden and workflow complexity. He has >50 publications in this field, and has been awarded several (personal) scientific and valorisation grants including VENI (interventional MRI), IMDI ZonMw (MRI-based radiotherapy planning), TTW Take-off phase I and II (commercialization of BoneMRI) and TTW Smart Industry (Deep learning-based image synthesis for orthopedics), NWO KIEM (BoneMRI in the shoulder) and Eurostars (additive manufacturing for orthopedics).
Peter Seevinck is co-founder of MRIguidance B.V., a company that commercializes BoneMRI, the first medical imaging technique that visualizes both bone and soft tissue, without the need for hazardous radiation. BoneMRI renders MRI a one-stop-shop workflow both for diagnostic/prognostic purposes as well as for innovative surgical purposes (e.g. pre-operative planning, navigation, virtual/augmented reality and robotics). For the patient such a one-stop-shop approach could lead to less radiological examinations, less hospital visits and a lower radiation burden. “With the CE marking of BoneMRI in 2019 an important milestone has been reached, as this opens the door towards widespread usage for the benefit of the patient”.
University Medical Center Utrecht
Heidelberglaan 100
Q.02.4.45
3584 CX Utrecht
The Netherlands
Publications
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Evaluation of MRI technologies for surgical spine planning and navigation
Feb 2025 in European Spine Journal -
A multipurpose, adolescent idiopathic scoliosis-specific, short MRI protocol: A feasibility study in volunteers
Aug 2024 in European Journal of Radiology 177 -
Magnetic resonance imaging-based bone imaging of the lower limb: Strategies for generating high-resolution synthetic computed tomography
Apr 2024 in Journal of Orthopaedic Research 42 (4), p. 843-854 -
Maturation of the vertebral ring apophysis is delayed in girls with adolescent idiopathic scoliosis compared to the normal population
Nov 2024 in Spine Deformity 12 (6), p. 1631-1637 -
Automatic generation of subject-specific finite element models of the spine from magnetic resonance images
Sep 2023 in Frontiers in bioengineering and biotechnology 11 -
Automatic Assessment of Lower-Limb Alignment from Computed Tomography
May 2023 in The Journal of bone and joint surgery. American volume 105 (9), p. 700-712 -
Impact of bone and cartilage segmentation from CT and MRI on both bone forearm osteotomy planning
Dec 2023 in International Journal of Computer Assisted Radiology and Surgery 18 (12), p. 2307-2318 -
The three-dimensional coupling mechanism in scoliosis and its consequences for correction
Nov 2023 in Spine Deformity 11 (6), p. 1509-1516 -
Correction: The three-dimensional coupling mechanism in scoliosis and its consequences for correction (Spine Deformity, (2023), 11, 6, (1509-1516), 10.1007/s43390-023-00732-8)
Nov 2023 in Spine Deformity 11 (6), p. 1553 -
MRI-based synthetic CT in the detection of knee osteoarthritis: Comparison with CT
Nov 2023 in Journal of Orthopaedic Research 41 (11), p. 2530-2539 -
Statistical shape model of the talus bone morphology: A comparison between impinged and nonimpinged ankles
Jan 2023 in Journal of Orthopaedic Research 41 (1), p. 183-195 -
Bone visualization of the cervical spine with deep learning-based synthetic CT compared to conventional CT: A single-center noninferiority study on image quality
Sep 2022 in European Journal of Radiology 154 p. 1-9 -
Magnetic Resonance Imaging Versus Computed Tomography for Three-Dimensional Bone Imaging of Musculoskeletal Pathologies: A Review
Jul 2022 in Journal of Magnetic Resonance Imaging 56 (1), p. 11-34 -
Synthetic CT for the planning of MR-HIFU treatment of bone metastases in pelvic and femoral bones: a feasibility study
Jul 2022 in European Radiology 32 (7), p. 4537-4546 -
Patient-specific 3D-printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model
May 2022 in Journal of Orthopaedic Research 40 (5), p. 1154-1162 -
MRI-based synthetic CT shows equivalence to conventional CT for the morphological assessment of the hip joint
Apr 2022 in Journal of Orthopaedic Research 40 (4), p. 954-964 -
Patient-specific 3D-printed shelf implant for the treatment of hip dysplasia tested in an experimental animal pilot in canines
Feb 2022 in Scientific Reports 12 (1), -
Good long-term outcomes of the hip Chiari osteotomy in adolescents and adults with hip dysplasia: a systematic review
Feb 2022 in Acta Orthopaedica 93 p. 296-302 -
Efficient cascaded V-net optimization for lower extremity CT segmentation validated using bone morphology assessment
Dec 2022 in Journal of Orthopaedic Research 40 (12), p. 2894-2907 -
CT to MR registration of complex deformations in the knee joint through dual quaternion interpolation of rigid transforms
Sep 2021 in Physics in medicine and biology 66 (17), -
Ossification and Fusion of the Vertebral Ring Apophysis as an Important Part of Spinal Maturation
Aug 2021 in Journal of Clinical medicine 10 (15), p. 1-10 -
3D-printed saw guides for lower arm osteotomy, a comparison between a synthetic CT and CT-based workflow
Apr 2021 in 3D Printing in Medicine 7 (1), p. 1-12 -
Multiple-echo steady-state (MESS): Extending DESS for joint T2 mapping and chemical-shift corrected water-fat separation
Dec 2021 in Magnetic Resonance in Medicine 86 (6), p. 3156-3165 -
Magnetic resonance imaging-based synthetic computed tomography of the lumbar spine for surgical planning: a clinical proof-of-concept
Jan 2021 in Neurosurgical Focus [E] 50 (1), p. 1-7 -
Deep learning-based MR-to-CT synthesis: The influence of varying gradient echo-based MR images as input channels
Apr 2020 in Magnetic Resonance in Medicine 83 (4), p. 1429-1441 -
Deep learning-enabled MRI-only photon and proton therapy treatment planning for paediatric abdominal tumours
Dec 2020 in Radiotherapy & Oncology 153 p. 220-227 -
Visualization of gold fiducial markers in the prostate using phase-cycled bSSFP imaging for MRI-only radiotherapy
Sep 2019 in Physics in Medicine and Biology 64 (18), p. 185001 -
Dosimetric evaluation of synthetic CT for head and neck radiotherapy generated by a patch-based three-dimensional convolutional neural network
Sep 2019 in Medical Physics 46 (9), p. 4095-4104 -
SMART tracking: Simultaneous anatomical imaging and real-time passive device tracking for MR-guided interventions
Aug 2019 in Physica medica 64 p. 252-260 -
Active tracked intramyocardial catheter injections for regenerative therapy with real-time MR guidance: feasibility in the porcine heart
Jul 2019 in EuroIntervention 15 (4), p. e336-e339 -
Reducing distortions in echo-planar breast imaging at ultrahigh field with high-resolution off-resonance maps
Jul 2019 in Magnetic Resonance in Medicine 82 (1), p. 425-435 -
GANs covert CBCT to CT for head-neck, lung and breast: paired vs unpaired; single-site vs generic
Apr 2019 in Radiotherapy and Oncology 133 p. S1105-S1106 -
MRI artifact simulation for clinically relevant MRI sequences for guidance of prostate HDR brachytherapy
Apr 2019 in Physics in Medicine and Biology 64 (9), p. 095006 -
Synthetic CT generation for Head and Neck radiotherapy by a 3D convolutional neural network
Apr 2019 in Radiotherapy and Oncology 133 p. S268-S269 -
isoPhasor: a generic and precise marker visualization, localization, and quantification method based on phase saddles in 3D MR imaging
Mar 2019 in Magnetic Resonance in Medicine 81 (3), p. 2038-2051 -
The anterior longitudinal ligament in diffuse idiopathic skeletal hyperostosis: ossified or displaced?
Sep 2018 in Journal of Orthopaedic Research 36 (9), p. 2491-2496 -
Dose evaluation of fast synthetic-CT generation using a generative adversarial network for general pelvis MR-only radiotherapy
Sep 2018 in Physics in Medicine and Biology 63 (18), p. 1-11 -
Feasibility of magnetic resonance imaging-only rectum radiotherapy with a commercial synthetic computed tomography generation solution
Jul 2018 in Physics and Imaging in Radiation Oncology 7 p. 58-64 -
Evaluation of gold fiducial marker manual localisation for magnetic resonance-only prostate radiotherapy
Jun 2018 in Radiation Oncology [E] 13 (1), p. 105 -
MRI Visualization of Injectable Ureidopyrimidinone Hydrogelators by Supramolecular Contrast Agent Labeling
Jun 2018 in Advanced Healthcare Materials 7 (11), -
OC-029: MR-based synthetic CT with conditional Generative Adversarial Network for prostate RT planning
Apr 2018 in Radiotherapy & Oncology 127 p. S150-S151 -
EP-2079: Feasibility of MR-only rectum radiotherapy using a commercial prostate sCT generation solution
Apr 2018 in Radiotherapy & Oncology 127 p. S1140-S1141 -
OC-0293: Dosimetric evaluation of deep learning based synthetic-CT generation for MR-only brain radiotherapy
Apr 2018 in Radiotherapy & Oncology 127 p. S151-S151 -
MR-based source localization for MR-guided HDR brachytherapy
Apr 2018 in Physics in Medicine and Biology 63 (8), p. 1-13 -
Development and Testing of a Magnetic Resonance (MR) Conditional Afterloader for Source Tracking in Magnetic Resonance Imaging-Guided High-Dose-Rate (HDR) Brachytherapy
Nov 2018 in International Journal of Radiation Oncology Biology Physics 102 (4), p. 960-968 -
MR-Only Brain Radiation Therapy: Dosimetric Evaluation of Synthetic CTs Generated by a Dilated Convolutional Neural Network
Nov 2018 in International Journal of Radiation Oncology Biology Physics 102 (4), p. 801-812 -
PO-0966: Translation of a certified MR-only synthetic CT solution for prostate from photon to proton therapy
2018 in Radiotherapy & Oncology 127 p. S531-S532 -
Magnetic resonance imaging of local and remote vascular remodelling after experimental stroke
Aug 2017 in Journal of Cerebral Blood Flow and Metabolism 37 (8), p. 2768-2779 -
Multispectral 3D phase-encoded turbo spin-echo for imaging near metal: Limitations and possibilities demonstrated by simulations and phantom experiments
Jun 2017 in Magnetic Resonance Imaging 39 p. 31-43 -
Manually controlled steerable needle for MRI-guided percutaneous interventions
Feb 2017 in Medical & Biological Engineering & Computing 55 (2), p. 235-244 -
Feasibility of MR-only proton dose calculations for prostate cancer radiotherapy using a commercial pseudo-CT generation method
Nov 2017 in Physics in Medicine and Biology 62 (24), p. 9159–9176 -
Fast Fourier-based simulation of off-resonance artifacts in steady-state gradient echo MRI applied to metal object localization
Nov 2017 in Magnetic Resonance in Medicine 78 (5), p. 2035-2041 -
Evaluation of an automatic MR-based gold fiducial marker localisation method for MR-only prostate radiotherapy
Oct 2017 in Physics in Medicine and Biology 62 (20), p. 7981-8002 -
Challenges in MR-only seed localization for postimplant dosimetry in permanent prostate brachytherapy
Oct 2017 in Medical Physics 44 (10), p. 5051-5060 -
Quantification of confounding factors in MRI-based dose calculations as applied to prostate IMRT
Jan 2017 in Physics in Medicine and Biology 62 (3), p. 948-965 -
Monte Carlo study of the impact of a magnetic field on the dose distribution in MRI-guided HDR brachytherapy using Ir-192
Aug 2016 in Physics in Medicine and Biology 61 (18), p. 6791-6807 -
MO-FG-CAMPUS-JeP2-04: Comparison Study for CT and MR-Only Prostate IMRT Treatment Planning: A Framework for the Estimation of Relative Contribution of Body Contour Discrepancies Tissue Stratification and HU-RED Conversion to the Overall Dose Difference
Jun 2016 in Medical Physics 43 (6), p. 3721-3722 -
Evaluation of Variable Density and Data-Driven K-Space Undersampling for Compressed Sensing Magnetic Resonance Imaging
Jun 2016 in Investigative Radiology 51 (6), p. 410-419 -
A Dixon Based Pseudo-CT Generation Method for MR-Only Radiotherapy Treatment Planning of the Pelvis and Head and Neck
Jul 2015 in Medical Physics 42 (6), p. 3316 -
Geometrically undistorted MRI in the presence of field inhomogeneities using compressed sensing accelerated broadband 3D phase encoded turbo spin-echo imaging
Jan 2015 in Physics in Medicine and Biology 60 (2), p. 615-631 -
Simultaneous R2 *, R2 , and R2 ' quantification by combining S0 estimation of the free induction decay with a single spin echo: A single acquisition method for R2 insensitive quantification of holmium-166-loaded microspheres
Jan 2015 in Magnetic Resonance in Medicine 73 (1), p. 273-283 -
19F MRSI of capecitabine in the liver at 7T using broadband transmit-receive antennas and dual-band RF pulses
2015 in NMR in Biomedicine 28 (11), p. 1433-1442 -
Holmium-lipiodol-alginate microspheres for fluoroscopy-guided embolotherapy and multimodality imaging
2015 in International Journal of Pharmaceutics 482 (1-2), p. 47-53 -
SU-E-J-131: Automatic Detection of Gold Fiducial Markers On MR Images Using the RASOR Technique
Jun 2014 in Medical Physics 41 (6), p. 186 -
Detecting breast microcalcifications with high-field MRI
2014 in NMR in Biomedicine 27 (5), p. 539-546 -
In vivo dosimetry based on SPECT and MR imaging of 166Ho-microspheres for treatment of liver malignancies
2013 in Journal of Nuclear Medicine 54 (12), p. 2093-2100 -
On the utility of spectroscopic imaging as a tool for generating geometrically accurate MR images and parameter maps in the presence of field inhomogeneities and chemical shift effects
2013 in Magnetic Resonance Imaging 31 (1), p. 86-95 -
Microbrachytherapy using holmium-166 acetylacetonate microspheres: A pilot study in a spontaneous cancer animal model
2013 in Brachytherapy 12 (2), p. 171-177 -
MRI-based biodistribution assessment of holmium-166 poly(L-lactic acid) microspheres after radioembolisation
2013 in European Radiology 23 (3), p. 827-835 -
Alginate-lanthanide microspheres for MRI-guided embolotherapy
2013 in Acta Biomaterialia 9 (1), p. 4681-4687 -
Intratumoral administration of holmium-166 acetylacetonate microspheres: antitumor efficacy and feasibility of multimodality imaging in renal cancer.
2013 in PLoS ONE [E] 8 (1), p. e52178 -
A dual-plane co-RASOR technique for accurate and rapid tracking and position verification of an Ir-192 source for single fraction HDR brachytherapy
2013 in Physics in Medicine and Biology 58 (21), p. 7829-2839 -
Center-out radial sampling with off-resonant reconstruction for efficient and accurate localization of punctate and elongated paramagnetic structures
2013 in Magnetic Resonance in Medicine 69 (6), p. 1611-1622 -
Magnetic resonance imaging-based radiation-absorbed dose estimation of 166Ho microspheres in liver radioembolization
Jul 2012 in International Journal of Radiation Oncology Biology Physics 83 (3), -
Selective depiction of susceptibility transitions using Laplace-filtered phase maps
2012 in Magnetic Resonance Imaging 30 (5), p. 601-609 -
Quantification of holmium-166 loaded microspheres: Estimating high local concentrations using a conventional multiple gradient echo sequence with S(0) -fitting
2012 in Journal of Magnetic Resonance Imaging 35 (6), p. 1453-1461 -
Towards inherently distortion-free MR images for image-guided radiotherapy on an MRI accelerator
2012 in Physics in Medicine and Biology 57 (5), p. 1349-1358 -
Magnetic resonance imaging-based radiation-absorbed dose estimation of (166)ho microspheres in liver radioembolization
2012 in International Journal of Radiation Oncology Biology Physics 83 (3), p. e437-e444 -
Highly localized positive contrast of small paramagnetic objects using 3D center-out radial sampling with off-resonance reception
2011 in Magnetic Resonance in Medicine 65 (1), p. 146-156 -
Holmium nanoparticles: preparation and in vitro characterization of a new device for radioablation of solid malignancies
2010 in Pharmaceutical Research 27 (10), p. 2205-2212 -
Magnetic resonance imaging of brain angiogenesis after stroke
2010 in Angiogenesis 13 (2), p. 101-111 -
Holmium-166 poly(L-lactic acid) microsphere radioembolisation of the liver: technical aspects studied in a large animal model
2010 in European Radiology 20 (4), p. 862-869 -
Microspheres with Ultrahigh Holmium Content for Radioablation of Malignancies
2009 in Pharmaceutical Research 26 (6), p. 1371-1378 -
Clinical effects of transcatheter hepatic arterial embolization with holmium-166 poly(L: -lactic acid) microspheres in healthy pigs
2008 in European Journal of Nuclear Medicine and Molecular Imaging 35 (7), p. 1259-1271 -
FID sampling superior to spin echo sampling for T2*-based quantification of holmium-loaded microspheres: Theory and experiment
2008 in Magnetic Resonance in Medicine 60 p. 1466-1476 -
Factors affecting the sensitivity and detection limits of MRI, CT, and SPECT for multimodal diagnostic and therapeutic agents
2007 in Anti-cancer Agents in Medicinal Chemistry 7 (3), p. 317-334