Alexander Leemans is a physicist who received his Ph.D. in 2006 at the University of Antwerp, Belgium. From 2007 to 2009, he worked as a postdoctoral researcher at the Cardiff University Brain Research Imaging Center (CUBRIC), Cardiff University, Wales, United Kingdom. In 2009, he joined the Image Sciences Institute (ISI), University Medical Center Utrecht, the Netherlands, where he currently holds a tenured faculty position as Associate Professor. His current research interests include modeling, processing, visualizing and analyzing diffusion MRI data for investigating microstructural and architectural tissue organization. He heads the PROVIDI Lab and is the developer of ExploreDTI, which is a graphical toolbox for investigating diffusion MRI data.
Research line
Diffusion MRI
Most recent key publications
1: C. Lebel, L. Walker, A. Leemans, L. Phillips, C. Beaulieu, "Microstructural Maturation of the Human Brain from Childhood to Adulthood", NeuroImage, 2008, nr. 3, vol. 40, pp. 1044-1055
2: A. Leemans, D.K. Jones, "The B-matrix must be rotated when correcting for subject motion in DTI data", Magnetic Resonance in Medicine, 2009, nr. 1, vol. 62, pp. 1336-1349
3: J.D. Tournier, S. Mori, A. Leemans, "Diffusion tensor imaging and beyond", Magnetic Resonance in Medicine, 2011, nr. 6, vol. 65, pp. 1532-1556
4: B. Jeurissen, A. Leemans, J.D. Tournier, D.K. Jones, J. Sijbers, "Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion MRI", Human Brain Mapping, 2013, nr. 11, vol. 34, pp. 2747-2766
5: S.B. Vos, D.K. Jones, M.A. Viergever, A. Leemans, "Partial volume effect as a hidden covariate in DTI analyses", NeuroImage, 2011, nr. 4, vol. 55, pp. 1566-1576
University Medical Center Utrecht
Heidelberglaan 100
Q.02.4.45
3584 CX Utrecht
The Netherlands
Publications
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Vigabatrin-associated brain magnetic resonance imaging abnormalities and clinical symptoms in infants with tuberous sclerosis complex
Feb 2025 in Epilepsia 66 (2), p. 356-368 -
Global Challenges After a Global Challenge: Lessons Learned from the COVID-19 Pandemic
Sep 2024 in Advances in Experimental Medicine and Biology 1457 p. 1-31 -
Methodological considerations on diffusion MRI tractography in infants aged 0–2 years: a scoping review
Aug 2024 in Pediatric Research -
Dominance of Tau Burden in Cortical Over Subcortical Regions Mediates Glymphatic Activity and Clinical Severity in PSP
May 2024 in Clinical Nuclear Medicine 49 (5), p. 387-396 -
Quantitative metrics commonly derived from diffusion tractography covary with streamline length: a characterization and method of adjustment
Dec 2024 in Brain Structure and Function 229 (9), p. 2431–2444 -
Clinical use-cases and implementation guidelines for the development of valuable AI
Dec 2024 in EJC Paediatric Oncology 4 -
Ventral and dorsal aspects of the inferior frontal-occipital fasciculus support verbal semantic access and visually-guided behavioural control
Jan 2024 in Brain structure & function 229 (1), p. 207-221 -
Neurological soft signs in adolescents are associated with brain structure
May 2023 in Cerebral Cortex 33 (9), p. 5547-5556 -
Mean kurtosis-Curve (MK-Curve) correction improves the test–retest reproducibility of diffusion kurtosis imaging at 3 T
Mar 2023 in NMR in Biomedicine 36 (3), p. 1-17 -
Reconstruction of the Corticospinal Tract in Patients with Motor-Eloquent High-Grade Gliomas Using Multilevel Fiber Tractography Combined with Functional Motor Cortex Mapping
Mar 2023 in AJNR. American journal of neuroradiology 44 (3), p. 283-290 -
Anatomically informed multi-level fiber tractography for targeted virtual dissection
Feb 2023 in Magma - Magnetic Resonance Materials In Physics Biology And Medicine 36 (1), p. 79-93 -
Neurological soft signs are associated with reduced medial-lateral postural control in adolescent athletes
Feb 2023 in Journal of the Neurological Sciences 445 -
Quantitative diffusion-weighted MRI response assessment in rhabdomyosarcoma: an international retrospective study on behalf of the European paediatric Soft tissue sarcoma Study Group Imaging Committee
Nov 2023 in Pediatric radiology 53 (12), p. 2539-2551 -
Methodological considerations on segmenting rhabdomyosarcoma with diffusion-weighted imaging—What can we do better?
Jan 2023 in Insights into Imaging 14 (1), p. 1-15 -
Insights from the IronTract challenge: Optimal methods for mapping brain pathways from multi-shell diffusion MRI
Aug 2022 in NeuroImage 257 p. 1-17 -
Improved neonatal brain MRI segmentation by interpolation of motion corrupted slices
May 2022 in Journal of Neuroimaging 32 (3), p. 480-492 -
Impact of thresholding on the consistency and sensitivity of diffusion MRI-based brain networks in patients with cerebral small vessel disease
May 2022 in Brain and Behavior 12 (5), p. 1-16 -
REPIMPACT - a prospective longitudinal multisite study on the effects of repetitive head impacts in youth soccer
Feb 2022 in Brain Imaging and Behavior 16 (1), p. 492-502 -
Topology of diffusion changes in corpus callosum in Alzheimer's disease: An exploratory case-control study
Nov 2022 in Frontiers in Neurology 13 p. 1-11 -
Sensory processing sensitivity and axonal microarchitecture: identifying brain structural characteristics for behavior
Nov 2022 in Brain Structure and Function 227 (8), p. 2769-2785 -
Improved sensitivity and precision in multicentre diffusion MRI network analysis using thresholding and harmonization
Oct 2022 in NeuroImage. Clinical 36 -
Cross-site harmonization of multi-shell diffusion MRI measures based on rotational invariant spherical harmonics (RISH)
Oct 2022 in NeuroImage 259 p. 1-12 -
Association between Motor Planning and the Frontoparietal Network in Children: An Exploratory Multimodal Study
Oct 2022 in Journal of the International Neuropsychological Society 28 (9), p. 926-936 -
Neuroanatomical markers of psychotic experiences in adolescents: A machine-learning approach in a longitudinal population-based sample
2022 in NeuroImage. Clinical 34 p. 1-9 -
Association of Superficial White Matter Alterations with Cerebrospinal Fluid Biomarkers and Cognitive Decline in Neurodegenerative Dementia
2022 in Journal of Alzheimer's Disease 85 (1), p. 431-442 -
Proceedings of the 13th International Newborn Brain Conference: Neuro-imaging studies
2022 in Journal of neonatal-perinatal medicine 15 (2), p. 389-409 -
White matter microstructure of the neural emotion regulation circuitry in mild traumatic brain injury
May 2021 in European Journal of Neuroscience 53 (10), p. 3463-3475 -
The effect of gradient nonlinearities on fiber orientation estimates from spherical deconvolution of diffusion magnetic resonance imaging data
Feb 2021 in Human Brain Mapping 42 (2), p. 367-383 -
Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?
Nov 2021 in NeuroImage 243 p. 1-18 -
Fiber orientation distribution from diffusion MRI: Effects of inaccurate response function calibration
Nov 2021 in Journal of Neuroimaging 31 (6), p. 1082-1098 -
Diffusion kurtosis imaging of white matter in bipolar disorder
Nov 2021 in Psychiatry Research - Neuroimaging 317 p. 1-9 -
Indices of callosal axonal density and radius from diffusion MRI relate to upper and lower limb motor performance
Nov 2021 in NeuroImage 241 p. 1-12 -
Dose-dependent volume loss in subcortical deep grey matter structures after cranial radiotherapy
Jan 2021 in Clinical and translational radiation oncology 26 p. 35-41 -
Diffusion MRI harmonization enables joint-analysis of multicentre data of patients with cerebral small vessel disease
Jan 2021 in NeuroImage: Clinical 32 p. 1-14 -
Iranian Brain Imaging Database: A Neuropsychiatric Database of Healthy Brain
Jan 2021 in Basic and clinical neuroscience 12 (1), p. 115-132 -
Generalized Richardson-Lucy (GRL) for analyzing multi-shell diffusion MRI data
Sep 2020 in NeuroImage 218 -
Structural Network Analysis Using Diffusion MRI Tractography in Parkinson's Disease and Correlations With Motor Impairment
Sep 2020 in Frontiers in Neurology 11 p. 841 -
Indirect frontocingulate structural connectivity predicts clinical response to accelerated rTMS in major depressive disorder
Jul 2020 in Journal of Psychiatry and Neuroscience 45 (4), p. 243-252 -
Effect of radiation therapy on cerebral cortical thickness in glioma patients: Treatment-induced thinning of the healthy cortex
Jul 2020 in Neuro-oncology advances 2 (1), -
Reduced hippocampal volume in adolescents with psychotic experiences: A longitudinal population-based study
Jun 2020 in PLoS ONE 15 (6), p. 1-13 -
Variability in the analysis of a single neuroimaging dataset by many teams
Jun 2020 in Nature 582 (7810), p. 84-88 -
A diffusion kurtosis imaging analysis of white matter microstructural differences in bipolar disorder
Jun 2020 in Bipolar Disorders 22 (S1), p. 17-18 -
Regions of white matter abnormalities in the arcuate fasciculus in veterans with anger and aggression problems
May 2020 in Brain structure & function 225 (4), p. 1401-1411 -
Effect of Fixed-Density Thresholding on Structural Brain Networks: A Demonstration in Cerebral Small Vessel Disease
Apr 2020 in Brain Connectivity 10 (3), p. 121-133 -
Perinatal thalamic injury: MRI predictors of electrical status epilepticus in sleep and long-term neurodevelopment
Apr 2020 in NeuroImage. Clinical 26 -
Early prediction of unilateral cerebral palsy in infants at risk: MRI versus the hand assessment for infants
Apr 2020 in Pediatric Research 87 (5), p. 932-939 -
Data-Driven Identification of the Regions of Interest for Fiber Tracking in Patients with Brain Tumors
Nov 2020 in World Neurosurgery 143 p. e275-e284 -
Harmonization of diffusion MRI data sets with adaptive dictionary learning
Nov 2020 in Human Brain Mapping 41 (16), p. 4478-4499 -
The YOUth cohort study: MRI protocol and test-retest reliability in adults
Oct 2020 in Developmental Cognitive Neuroscience 45 p. 1-15 -
Automated characterization of noise distributions in diffusion MRI data
Oct 2020 in Medical Image Analysis 65 -
Psychotic experiences in childhood are associated with increased structural integrity of the left arcuate fasciculus – A population-based case-control study
Jan 2020 in Schizophrenia Research 215 p. 378-384 -
Tractography reproducibility challenge with empirical data (TraCED): The 2017 ISMRM diffusion study group challenge
Jan 2020 in Journal of Magnetic Resonance Imaging 51 (1), p. 234-249 -
The adverse effect of gradient nonlinearities on diffusion MRI: From voxels to group studies
Jan 2020 in NeuroImage 205 -
Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network
Sep 2019 in Journal of the American Geriatrics Society 67 (9), p. 1880-1887 -
Any Radiation Dose to the Hippocampus Leads to Local Volume Loss in a Dose-Time-Dependent Way
Sep 2019 in International Journal of Radiation Oncology Biology Physics 105 (1), p. E104-E105 -
Magnetic resonance imaging of the cervical spinal cord in spinal muscular atrophy
Sep 2019 in Neuroimage: Clinical [E] 24 -
Evaluation of the 3D fractal dimension as a marker of structural brain complexity in multiple-acquisition MRI
Aug 2019 in Human Brain Mapping 40 (11), p. 3299-3320 -
Cross-scanner and cross-protocol diffusion MRI data harmonisation: A benchmark database and evaluation of algorithms
Jul 2019 in NeuroImage 195 p. 285-299 -
Changes in cortical thickness and volume after cranial radiation treatment: A systematic review
Jun 2019 in Radiotherapy and Oncology 135 p. 33-42 -
Diffusion tensor imaging biomarkers to predict motor outcomes in stroke: A narrative review
May 2019 in Frontiers in Neurology 10 (MAY), p. 445 -
Identifying No Fly Zones to prevent long-term thinning of the cerebral cortex in glioma after RT
Apr 2019 in Radiotherapy and Oncology 133 p. S82-S83 -
The superoanterior fasciculus (SAF): A novel white matter pathway in the human brain?
Mar 2019 in Frontiers in Neuroanatomy [E] 13 p. 24 -
Reproducibility and intercorrelation of graph theoretical measures in structural brain connectivity networks
Feb 2019 in Medical Image Analysis 52 p. 56-67 -
Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy
Feb 2019 in Neurology 92 (9), p. E933-E943 -
On the sensitivity of the diffusion MRI signal to brain activity in response to a motor cortex paradigm
Dec 2019 in Human Brain Mapping 40 (17), p. 5069-5082 -
Reducing variability in along-tract analysis with diffusion profile realignment
Oct 2019 in NeuroImage 199 p. 663-679 -
Widespread white matter connectivity abnormalities in narcolepsy type 1: A diffusion tensor imaging study
Jan 2019 in NeuroImage: Clinical 24 p. 101963 -
Weight loss, behavioral change, and structural neuroplasticity in children with obesity through a multidisciplinary treatment program
Jan 2019 in Human Brain Mapping 40 (1), p. 137-150 -
Microstructural White Matter Abnormalities and Cognitive Impairment After Aneurysmal Subarachnoid Hemorrhage
Sep 2018 in Stroke 49 (9), p. 2040-2045 -
White matter network alterations in patients with depersonalization/derealization disorder
Sep 2018 in Journal of Psychiatry and Neuroscience 43 (5), p. 347-357 -
A Different Brain: Anomalies of functional and structural connections in Williams syndrome
Sep 2018 in Frontiers in Neurology 9 (sep), p. 1-10 -
Diffusion MRI-based cortical connectome reconstruction: dependency on tractography procedures and neuroanatomical characteristics
Jun 2018 in Brain Structure and Function 223 (5), p. 2269-2285 -
Mild cerebellar injury does not significantly affect cerebral white matter microstructural organization and neurodevelopmental outcome in a contemporary cohort of preterm infants
May 2018 in Pediatric Research 83 ( 5), p. 1004-1010 -
Microstructure of Strategic White Matter Tracts and Cognition in Memory Clinic Patients with Vascular Brain Injury
Apr 2018 in Dementia and Geriatric Cognitive Disorders 44 (5-6), p. 268-282 -
Changes in brain morphology and microstructure in relation to early brain activity in extremely preterm infants
Apr 2018 in Pediatric Research 83 (4), p. 834-842 -
Post-mortem diffusion MRI of the cervical spine and its nerve roots
Mar 2018 in Journal of Forensic Radiology and Imaging 12 p. 50-56 -
Abnormal fronto-parietal white matter organisation in the superior longitudinal fasciculus branches in autism spectrum disorders
Mar 2018 in European Journal of Neuroscience 47 (6), p. 652-661 -
Evidence for Training-Dependent Structural Neuroplasticity in Brain-Injured Patients: A Critical Review
Feb 2018 in Neurorehabilitation and Neural Repair 32 (2), p. 99-114 -
Recovery from chemotherapy-induced white matter changes in young breast cancer survivors?
Feb 2018 in Brain Imaging and Behavior 12 (1), p. 64-77 -
Associations between prenatal, childhood, and adolescent stress and variations in white-matter properties in young men
Nov 2018 in NeuroImage 182 p. 389-397 -
A robust deconvolution method to disentangle multiple water pools in diffusion MRI
Nov 2018 in NMR in Biomedicine 31 (11), -
Fast and accurate Slicewise OutLIer Detection (SOLID) with informed model estimation for diffusion MRI data
Nov 2018 in NeuroImage 181 p. 331-346 -
Multicenter reproducibility study of diffusion MRI and fiber tractography of the lumbosacral nerves
Oct 2018 in Journal of Magnetic Resonance Imaging 48 (4), p. 951-963 -
Multiparametric quantitative MRI assessment of thigh muscles in limb-girdle muscular dystrophy 2A and 2B
Oct 2018 in Muscle & Nerve 58 (4), p. 550-558 -
White matter hyperintensity shape and location feature analysis on brain MRI; Proof of principle study in patients with diabetes
Jan 2018 in Scientific Reports 8 (1), p. 1-10 -
Effects of early nutrition and growth on brain volumes, white matter microstructure, and neurodevelopmental outcome in preterm newborns
Jan 2018 in Pediatric Research 83 (1), p. 102-110 -
Accelerated intermittent theta burst stimulation in major depression induces decreases in modularity: A connectome analysis
Jan 2018 in NETWORK NEUROSCIENCE 3 (1), p. 157-172 -
The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients
Jan 2018 in NeuroImage: Clinical 19 p. 963-969 -
Diffusion imaging markers of bipolar versus general psychopathology risk in youth at-risk
2018 in Neuropsychopharmacology 43 p. 2212-2220 -
Progressive microstructural changes of the occipital cortex in Huntington’s disease
2018 in Brain Imaging and Behavior 12 (6), p. 1786-1794 -
White matter maturation in the neonatal brain is predictive of school age cognitive capacities in children born very preterm
Sep 2017 in Developmental Medicine and Child Neurology 59 (9), p. 939-946 -
Anatomical integration and rich-club connectivity in euthymic bipolar disorder
Jul 2017 in Psychological Medicine 47 (9), p. 1609-1623 -
Quantifying the brain's sheet structure with normalized convolution
Jul 2017 in Medical Image Analysis 39 p. 162-177 -
Intravoxel incoherent motion modeling in the kidneys: Comparison of mono-, bi-, and triexponential fit
Jul 2017 in Journal of Magnetic Resonance Imaging 43 (1), p. 228–239 -
Learning Morse Code Alters Microstructural Properties in the Inferior Longitudinal Fasciculus: A DTI Study
Jul 2017 in Frontiers in Human Neuroscience 11 p. 1-9 -
"MASSIVE" Brain Dataset: Multiple Acquisitions for Standardization of Structural Imaging Validation and Evaluation
May 2017 in Magnetic Resonance in Medicine 77 (5), p. 1797-1809 -
MRI shows thickening and altered diffusion in the median and ulnar nerves in multifocal motor neuropathy
May 2017 in European Radiology 27 (5), p. 2216–2224 -
Transcallosal connectivity of the human cortical motor network
Apr 2017 in Brain Structure and Function 222 (3), p. 1243-1252 -
Structural and functional cortical connectivity mediating cross education of motor function
Mar 2017 in Journal of Neuroscience 37 (10), p. 2555-2564 -
Altered Wiring of the Human Structural Connectome in Adults with Mild Traumatic Brain Injury
Mar 2017 in Journal of Neurotrauma 34 (5), p. 1035-1044 -
Changes in Brain Structural Networks and Cognitive Functions in Testicular Cancer Patients Receiving Cisplatin-Based Chemotherapy
Dec 2017 in Journal of the National Cancer Institute 109 (12), -
The challenge of mapping the human connectome based on diffusion tractography
Nov 2017 in Nature Communications [E] 8 (1), -
The importance of correcting for signal drift in diffusion MRI
Jan 2017 in Magnetic Resonance in Medicine 77 (1), p. 285-299 -
The arcuate fasciculus network and verbal deficits in psychosis
2017 in Translational Neuroscience 8 (1), p. 117-126 -
Axon density and axon orientation dispersion in children born preterm
Sep 2016 in Human Brain Mapping 37 (9), p. 3080-3102 -
Small vessel disease and cognitive impairment: The relevance of central network connections
Jul 2016 in Human Brain Mapping 37 (7), p. 2446-2454 -
Diffusion tensor imaging of peripheral nerves in non-fixed post-mortem subjects
Jun 2016 in Forensic Science International 263 p. 139-146 -
PCA-based groupwise image registration for quantitative MRI
Apr 2016 in Medical Image Analysis 29 p. 65-78 -
Trade-off between angular and spatial resolutions in in vivo fiber tractography
Apr 2016 in NeuroImage 129 p. 117-132 -
Moderate and late preterm infants exhibit widespread brain white matter microstructure alterations at term-equivalent age relative to term-born controls
Mar 2016 in Brain Imaging and Behavior 10 (1), p. 41-49 -
Brain Connectomics of Visual-Motor Deficits in Children with Developmental Coordination Disorder
Feb 2016 in Journal of Pediatrics 169 p. 21-27e2 -
Multimodal MRI reveals structural connectivity differences in 22q11 deletion syndrome related to impaired spatial working memory
Dec 2016 in Human Brain Mapping 37 (12), p. 4689-4705 -
Alterations in brain white matter contributing to age-related slowing of task switching performance: The role of radial diffusivity and magnetization transfer ratio
Nov 2016 in Human Brain Mapping 37 (11), p. 4084-4098 -
Sheet Probability Index (SPI): Characterizing the geometrical organization of the white matter with diffusion MRI
Nov 2016 in NeuroImage 142 p. 260-279 -
White matter abnormalities and impaired attention abilities in children born very preterm
Jan 2016 in NeuroImage 124 p. 75-84 -
Choosing the polarity of the phase-encoding direction in diffusion MRI: Does it matter for group analysis?
2016 in Neuroimage: Clinical [E] 11 p. 539-547 -
Diffusion Tensor Imaging and Fiber Tractography in Children with Craniosynostosis Syndromes
Aug 2015 in American Journal of Neuroradiology 36 (8), p. 1558-1564 -
Data quality in diffusion tensor imaging studies of the preterm brain: a systematic review
Aug 2015 in Pediatric Radiology 45 (9), p. 1372-1381 -
Dynamics of the connectome in Huntington's disease: A longitudinal diffusion MRI study
Aug 2015 in Neuroimage: Clinical [E] 9 p. 32-43 -
Decoupling of structural and functional brain connectivity in older adults with white matter hyperintensities
Aug 2015 in NeuroImage 117 p. 222-229 -
White matter differences among adolescents reporting psychotic experiences: A population-based diffusion magnetic resonance imaging study
Jul 2015 in JAMA Psychiatry 72 (7), p. 668-677 -
Layered genetic control of DNA methylation and gene expression: A locus of multiple sclerosis in healthy individuals
Jun 2015 in Human Molecular Genetics 24 (20), p. 5733-5745 -
Diffusion tensor imaging of the auditory nerve in patients with long-term single-sided deafness
May 2015 in Hearing Research 323 p. 1-8 -
ADVANCED DIFFUSION IMAGING REVEALS EARLY WHITE MATTER BRAIN CHANGES IN ADOLESCENTS EXPERIENCING PSYCHOTIC SYMPTOMS
Mar 2015 in Schizophrenia Bulletin 41 p. S267-S268 -
Microstructural white matter tissue characteristics are modulated by homocysteine: A diffusion tensor imaging study
Feb 2015 in PLoS ONE [E] 10 (2), -
Long-term neural and physiological phenotyping of a single human
Dec 2015 in Nature Communications [E] 6 -
Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder
Dec 2015 in Molecular Autism [E] 6 -
Accelerated corpus callosum development in prematurity predicts improved outcome
Oct 2015 in Human Brain Mapping 36 (10), p. 3733-3748 -
Structural brain network analysis in families multiply affected with bipolar I disorder
Oct 2015 in Psychiatry Research - Neuroimaging 234 (1), p. 44-51 -
The effect of Gibbs ringing artifacts on measures derived from diffusion MRI
Oct 2015 in NeuroImage 120 p. 441-455 -
Seeing More by Showing Less: Orientation-Dependent Transparency Rendering for Fiber Tractography Visualization
Oct 2015 in PLoS ONE [E] 10 (10), -
Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome
Jan 2015 in Molecular Autism [E] 6 (4), -
Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy
Jan 2015 in Brain 138 (1), p. 179-188 -
Informed constrained spherical deconvolution (iCSD)
Jan 2015 in Medical Image Analysis 24 (1), p. 269-281 -
Recent advancements in diffusion MRI for investigating cortical development after preterm birth—potential and pitfalls
Jan 2015 in Frontiers in Human Neuroscience 8 (JAN), -
Effective electric fields along realistic DTI-based neural trajectories for modelling the stimulation mechanisms of TMS
Jan 2015 in Physics in Medicine and Biology 60 (2), p. 453-471 -
Bimanual motor deficits in older adults predicted by diffusion tensor imaging metrics of corpus callosum subregions
Jan 2015 in Brain Structure and Function 220 (1), p. 273-290 -
White matter structure in youth with behavioral and emotional dysregulation disorders a probabilistic tractographic study
Jan 2015 in JAMA Psychiatry 72 (4), p. 367-376 -
Neonatal DTI early after birth predicts motor outcome in preterm infants with periventricular hemorrhagic infarction
Jan 2015 in Pediatric Research 78 (3), p. 298-303 -
Microstructural brain abnormalities in Huntington's disease: A two-year follow-up
Jan 2015 in Human Brain Mapping 36 (6), p. 2061-2074 -
Hippocampal Disconnection in Early Alzheimer's Disease: A 7 Tesla MRI Study
2015 in Journal of Alzheimer's Disease 45 (4), p. 1247-1256 -
REKINDLE: Robust Extraction of Kurtosis INDices with Linear Estimation
2015 in Magnetic Resonance in Medicine 73 (2), p. 794-808 -
Hierarchical non-negative matrix factorization to characterize brain tumor heterogeneity using multi-parametric MRI
2015 in NMR in Biomedicine 28 (12), p. 1599-1624 -
White matter organization in relation to upper limb motor control in healthy subjects: exploring the added value of diffusion kurtosis imaging
Sep 2014 in Brain Structure and Function 219 (5), p. 1627-1638 -
Choice of diffusion tensor estimation approach affects fiber tractography of the fornix in preterm brain
Jun 2014 in American Journal of Neuroradiology 35 (6), p. 1219-1225 -
Multiple microbleeds are related to cerebral network disruptions in patients with early Alzheimer's disease
Jan 2014 in Journal of Alzheimer's Disease 38 (1), p. 211-221 -
Recursive calibration of the fiber response function for spherical deconvolution of diffusion MRI data
2014 in NeuroImage 86 p. 67-80 -
Automated correction of improperly rotated diffusion gradient orientations in diffusion weighted MRI
2014 in Medical Image Analysis 18 (7), p. 953-962 -
Methodological considerations on tract-based spatial statistics (TBSS)
2014 in NeuroImage 100 p. 358-369 -
Evaluating contextual processing in diffusion MRI: application to optic radiation reconstruction for epilepsy surgery
2014 in PLoS ONE [E] 9 (7), p. e101524 -
Automated longitudinal intra-subject analysis (ALISA) for diffusion MRI tractography
2014 in NeuroImage 86 p. 404-416 -
Hemispheric lateralization of topological organization in structural brain networks
2014 in Human Brain Mapping 35 (9), p. 4944-4957 -
Altered interhemispheric and temporal lobe white matter microstructural organization in severe chronic schizophrenia
2014 in Neuropsychopharmacology 39 (4), p. 944-954 -
Altered structural networks and executive deficits in traumatic brain injury patients
2014 in Brain Structure and Function 219 (1), p. 193-209 -
Structural neuroimaging correlates of allelic variation of the BDNF val66met polymorphism
2014 in NeuroImage 90 p. 280-289 -
Integrating diffusion kurtosis imaging, dynamic susceptibility-weighted contrast-enhanced MRI, and short echo time chemical shift imaging for grading gliomas
2014 in Neuro-Oncology 16 (7), p. 1010-1021 -
White matter microstructural abnormalities in families multiply affected with bipolar I disorder: a diffusion tensor tractography study
2014 in Psychological Medicine 10 (44), p. 2139-2150 -
Hoe magnetisme en diffusie kunnen bijdragen aan hersenonderzoek: toepassingen van diffusie-MRI-tractografie
2014 in Neuropraxis 18 (3), p. 92-105 -
Microstructural brain development between 30 and 40 weeks corrected age in a longitudinal cohort of extremely preterm infants
2014 in NeuroImage 103C p. 214-224 -
Isotropic non-white matter partial volume effects in constrained spherical deconvolution
2014 in Frontiers in Neuroinformatics [E] 8 p. 28 -
Diffusion tensor magnetic resonance imaging and fiber tractography of the sacral plexus in children with spina bifida
2014 in The Journal of Urology 192 (3), p. 927-933 -
Alterations in the optic radiations of very preterm children-Perinatal predictors and relationships with visual outcomes
2014 in Neuroimage: Clinical [E] 4 p. 145-153 -
Diffusion magnetic resonance imaging and fiber tractography: The state of the art and its potential impact on patient management
Jan 2013 in PET Clinics 8 (3), p. 279-293 -
Increased coherence of white matter fiber tract organization in adults with asperger syndrome: a diffusion tensor imaging study
2013 in Autism Research 6 (6), p. 642-650 -
Topological correlations of structural and functional networks in patients with traumatic brain injury
2013 in Frontiers in Human Neuroscience 7 p. 726 -
White matter differences in euthymic bipolar I disorder: a combined magnetic resonance imaging and diffusion tensor imaging voxel-based study
2013 in Bipolar Disorders 15 (4), p. 365-376 -
Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging
2013 in Human Brain Mapping 34 (11), p. 2747-2766 -
Assessment of global and regional diffusion changes along white matter tracts in Parkinsonian disorders by MR tractography
2013 in PLoS ONE [E] 8 (6), p. e66022 -
White matter and visuospatial processing in autism: a constrained spherical deconvolution tractography study
2013 in Autism Research 6 (5), p. 307-319 -
Disruption of cerebral networks and cognitive impairment in Alzheimer disease
2013 in Neurology 80 (15), p. 1370-1377 -
Diffusion tensor imaging metrics of the corpus callosum in relation to bimanual coordination: Effect of task complexity and sensory feedback
2013 in Human Brain Mapping 34 (1), p. 241-252 -
Does the use of hormonal contraceptives cause microstructural changes in cerebral white matter? Preliminary results of a DTI and tractography study
2013 in European Radiology 23 (1), p. 57-64 -
Variability in diffusion kurtosis imaging: Impact on study design, statistical power and interpretation
2013 in NeuroImage 76 p. 145-154 -
Limbic and callosal white matter changes in euthymic bipolar I disorder: an advanced diffusion magnetic resonance imaging tractography study
2013 in Biological Psychiatry 73 (2), p. 194-201 -
Reliability of two clinically relevant fiber pathways reconstructed with constrained spherical deconvolution
2013 in Magnetic Resonance in Medicine 70 (6), p. 1544-1556 -
Weighted linear least squares estimation of diffusion MRI parameters: Strengths, limitations, and pitfalls
2013 in NeuroImage 81 p. 335-346 -
Diffusion tensor MRI of chemotherapy-induced cognitive impairment in non-CNS cancer patients: a review
2013 in Brain Imaging and Behavior 7 (4), p. 409-435 -
Abnormal functional connectivity during visuospatial processing is associated with disrupted organisation of white matter in autism
2013 in Frontiers in Human Neuroscience 7 p. 434 -
Microstructural white matter abnormalities and cognitive functioning in type 2 diabetes: a diffusion tensor imaging study
2013 in Diabetes Care 36 (1), p. 137-144 -
Multi-fiber tractography visualizations for diffusion MRI data
2013 in PLoS ONE [E] 8 (11), p. e81453 -
Acquisition guidelines and quality assessment tools for analyzing neonatal diffusion tensor MRI data
2013 in American Journal of Neuroradiology 34 (8), p. 1496-1505 -
Reliability of the corticospinal tract and arcuate fasciculus reconstructed with DTI-based tractography: implications for clinical practice
2013 in European Radiology 23 (1), p. 28-36 -
Comprehensive framework for accurate diffusion MRI parameter estimation
2013 in Magnetic Resonance in Medicine 70 (4), p. 972-984 -
Disruption of the cerebral white matter network is related to slowing of information processing speed in patients with type 2 diabetes
2013 in Diabetes 62 (6), p. 2112-2115 -
Investigating the need of triggering the acquisition for infant diffusion MRI: A quantitative study including bootstrap statistics
2013 in NeuroImage 69 p. 198-205 -
Bimanual motor coordination in older adults is associated with increased functional brain connectivity - a graph-theoretical analysis
2013 in PLoS ONE [E] 8 (4), p. e62133 -
Uncertainty estimations for quantitative in vivo MRI T1 mapping
Nov 2012 in Journal of Magnetic Resonance 224 p. 53-60 -
Temporal association tracts and the breakdown of episodic memory in mild cognitive impairment
2012 in Neurology 79 (23), p. 2233-2240 -
Microstructural white matter abnormalities in type 2 diabetes mellitus: A diffusion tensor imaging study
2012 in NeuroImage 59 (2), p. 1098-1105 -
The influence of complex white matter architecture on the mean diffusivity in diffusion tensor MRI of the human brain
2012 in NeuroImage 59 (3), p. 2208-2216 -
Cortical network for gaze control in humans revealed using multimodal MRI
2012 in Cerebral Cortex 22 (4), p. 765-775 -
Uncertainty estimations for quantitative in vivo MRI T(1) mapping
2012 in Journal of Magnetic Resonance 224 p. 53-60 -
Architectural configuration and microstructural properties of the sacral plexus: A diffusion tensor MRI and fiber tractography study
2012 in NeuroImage 62 (3), p. 1792-1799 -
Brain connectivity and postural control in young traumatic brain injury patients: A diffusion MRI based network analysis
2012 in Neuroimage: Clinical [E] 1 p. 106-115 -
Longitudinal assessment of chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning
2012 in Journal of Clinical Oncology 30 (3), p. 274-281 -
Fronto-striatal circuitry and inhibitory control in autism: Findings from diffusion tensor imaging tractography
2012 in Cortex 48 (2), p. 183-193 -
Reduced fractional anisotropy in the uncinate fasciculus in patients with major depression carrying the met-allele of the Val66Met brain-derived neurotrophic factor genotype
2012 in American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 159 (5), p. 537-548 -
Cerebral white matter and neurodevelopment of preterm infants after coagulase-negative staphylococcal sepsis
2012 in Pediatric Critical Care Medicine 13 (6), p. 678-684 -
Microstructural organization of corpus callosum projections to prefrontal cortex predicts bimanual motor learning
2012 in Learning & Memory (Cold Spring Harbor, N.Y.) 19 (8), p. 351-357 -
Is there a common neuroanatomical substrate of language deficit between autism spectrum disorder and specific language impairment?
2012 in Cerebral Cortex 22 (10), p. 2263-2271 -
Graph analysis of functional brain networks for cognitive control of action in traumatic brain injury
2012 in Brain 135 (Pt 4), p. 1293-1307 -
A DTI-based model for TMS using the independent impedance method with frequency-dependent tissue parameters
2012 in Physics in Medicine and Biology 57 (8), p. 2169-2188 -
Diffusion Tensor Imaging of vascular Parkinsonism: Structural changes in cerebral white matter and the association with clinical severity
2012 in Archives of Neurology 69 (10), p. 1340-1348 -
Chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning in breast cancer patients
2011 in Human Brain Mapping 32 (3), p. 480-493 -
Differential corticospinal tract degeneration in homozygous ‘D90A’ SOD-1 ALS and sporadic ALS
2011 in Journal of Neurology, Neurosurgery and Psychiatry 82 (8), p. 843-849 -
Correlations between white matter integrity and motor function in traumatic brain injury patients
2011 in Neurorehabilitation and Neural Repair 25 (6), p. 492-502 -
A comparison of MR based segmentation methods for measuring brain atrophy progression
2011 in NeuroImage 54 (2), p. 760-768 -
Signal to noise ratio and uncertainty in diffusion tensor imaging at 1.5, 3.0, and 7.0 Tesla
2011 in Journal of Magnetic Resonance Imaging 33 (6), p. 1456-1463 -
The effect of template selection on diffusion tensor voxel based analysis results
2011 in NeuroImage 55 (2), p. 566-573 -
Probabilistic fiber tracking using the residual bootstrap with constrained spherical deconvolution
2011 in Human Brain Mapping 32 (3), p. 461-479 -
Bimanual coordination and corpus callosum microstructure in young adults with traumatic brain injury: a diffusion tensor imaging study
2011 in Journal of Neurotrauma 28 (6), p. 897-913 -
Construction of a stereotaxic DTI atlas with full diffusion tensor information for studying white matter maturation from childhood to adolescence using tractography-based segmentations
2010 in Human Brain Mapping 31 (3), p. 470-486 -
Brain-behavior relationships in young traumatic brain injury patients: fractional anisotropy measures are highly correlated with dynamic visuomotor tracking performance
2010 in Neuropsychologia 48 (5), p. 1472-1482 -
Comparing isotropic and anisotropic smoothing for voxel-based DTI analyses: A simulation study
2010 in Human Brain Mapping 31 (1), p. 98-114 -
Witte stof afwijkingen en intelligentie bij kinderen met tubereuze sclerose
2010 in Epilepsie september -
Brain-behavior relationships in young traumatic brain injury patients: DTI metrics are highly correlated with postural control
2010 in Human Brain Mapping 31 (7), p. 992-1002 -
Microstructural white matter changes in normal aging: a diffusion tensor imaging study with higher-order polynomial regression models
2010 in NeuroImage 49 (1), p. 32-43 -
Correlation of cognitive dysfunction and diffusion tensor MRI measures in patients with mild and moderate multiple sclerosis
2010 in Journal of Magnetic Resonance Imaging 31 (6), p. 1492-1498 -
The B-matrix must be rotated when correcting for subject motion in DTI data
Jun 2009 in Magnetic Resonance in Medicine 61 (6), p. 1336-1349 -
Quantitative diffusion tensor imaging in amyotrophic lateral sclerosis: revisited
2009 in Human Brain Mapping 30 (11), p. 3657-3675 -
Diffusion tensor imaging in a rat model of Parkinson's disease after lesioning of the nigrostriatal tract
2009 in NMR in Biomedicine 22 (7), p. 697-706 -
A diffusion tensor imaging group study of the spinal cord in multiple sclerosis patients with and without T2 spinal cord lesions
2009 in Journal of Magnetic Resonance Imaging 30 (1), p. 25-34 -
On the construction of a ground truth framework for evaluating voxel-based diffusion tensor MRI analysis methods
2009 in NeuroImage 46 (3), p. 692-707 -
Structural changes between seasons in the songbird auditory forebrain
2009 in Journal of Neuroscience 29 (43), p. 13557-13565 -
A tracking-based diffusion tensor imaging segmentation method for the detection of diffusion-related changes of the cervical spinal cord with aging
May 2008 in Journal of Magnetic Resonance Imaging 27 (5), p. 978-991 -
On the construction of an inter-subject diffusion tensor magnetic resonance atlas of the healthy human brain
Oct 2008 in NeuroImage 43 (1), p. 69-80 -
Microstructural Maturation of the Human Brain from Childhood to Adulthood
2008 in NeuroImage 40 (3), p. 1044-1055 -
Gender differences and age-related white matter changes of the human brain: a diffusion tensor imaging study
2008 in NeuroImage 39 (2), p. 566-577 -
Nonrigid coregistration of diffusion tensor images using a viscous fluid model and mutual information
Nov 2007 in IEEE Transactions on Medical Imaging 26 (11), p. 1598-1612 -
Influence of user-defined parameters on diffusion tensor tractography of the corticospinal tract
Jan 2007 in Neuroradiology Journal 20 (2), p. 139-147 -
In vivo diffusion tensor imaging (DTI) of brain subdivisions and vocal pathways in songbirds
2006 in NeuroImage 29 (3), p. 754-763 -
Multiscale white matter fiber tract coregistration: a new feature-based approach to align diffusion tensor data
2006 in Magnetic Resonance in Medicine 55 (6), p. 1414-1423 -
Mathematical framework for simulating diffusion tensor MR neural fiber bundles
2005 in Magnetic Resonance in Medicine 53 (4), p. 944-953