Hugo Kuijf is a senior scientist in artificial intelligence and (medical) image analysis.
Links:
Image Sciences Institute
University Medical Center Utrecht
Heidelberglaan 100
Room Q.02.4.45
3584 CX Utrecht
The Netherlands
email: h.kuijf@umcutrecht.nl
office: Q.02.4.36
phone: +31 88 75 58562
secretary: +31 88 75 57772
Publications
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Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
Feb 2025 in Neurobiology of Aging 146 p. 38-47 -
Tract-specific white matter hyperintensities and neuropsychiatric syndromes: a multicentre memory clinic study
Jan 2025 in Journal of Neurology, Neurosurgery and Psychiatry -
Influence of learned landmark correspondences on lung CT registration
Aug 2024 in Medical Physics 51 (8), p. 5321-5336 -
Three-Dimensional Morphological Change of Intracranial Aneurysms Before and Around Rupture
Jun 2024 in Neurosurgery 94 (6), p. 1211-1217 -
Anatomical Markers Associated With the Presence of Intracranial Aneurysms in Individuals Screened for Aneurysms
May 2024 in Stroke: Vascular and Interventional Neuroloy -
Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients
Apr 2024 in Alzheimer's and Dementia 20 (4), p. 2980-2989 -
Detectability and accuracy of computational measurements of in-silico and physical representations of enlarged perivascular spaces from magnetic resonance images
Mar 2024 in Journal of Neuroscience Methods 403 -
Graph convolutional networks for automated intracranial artery labeling
Feb 2024 in Journal of Medical Imaging 11 (1), -
NnU-Net versus mesh growing algorithm as a tool for the robust and timely segmentation of neurosurgical 3D images in contrast-enhanced T1 MRI scans
Feb 2024 in Acta Neurochirurgica 166 (1), -
Markers of amyloid-β deposition and burden of enlarged perivascular spaces in patients with cognitive impairment and small vessel disease
Dec 2024 in Journal of Alzheimer's disease : JAD 102 (4), p. 981-986 -
Deep-learning-based extraction of circle of Willis topology with anatomical priors
Dec 2024 in Scientific Reports 14 (1), -
Strategic white matter hyperintensity locations associated with post-stroke cognitive impairment: a multicenter study in 1568 stroke patients
Oct 2024 in International Journal of Stroke 19 (8), p. 916-924 -
Where is VALDO?: VAscular Lesions Detection and segmentatiOn challenge at MICCAI 2021
Jan 2024 in Medical Image Analysis 91 -
Influence of Comorbidity of Cerebrovascular Disease and Amyloid-on Alzheimer's Disease
2024 in Advances in Alzheimer's Disease p. 381-394 -
Bayesian modelling disentangles language versus executive control disruption in stroke
2024 in Brain communications 6 (3), -
Sex Differences in Poststroke Cognitive Impairment: A Multicenter Study in 2343 Patients With Acute Ischemic Stroke
Sep 2023 in Stroke 54 (9), p. 2296-2303 -
Neuroimaging standards for research into small vessel disease-advances since 2013
Jul 2023 in The Lancet. Neurology 22 (7), p. 602-618 -
Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients
Jun 2023 in Alzheimer's & Dementia 19 (6), p. 2420-2432 -
Disentangling poststroke cognitive deficits and their neuroanatomical correlates through combined multivariable and multioutcome lesion-symptom mapping
Apr 2023 in Human Brain Mapping 44 (6), p. 2266-2278 -
Carotid Artery Stenosis and Progression of Hemispheric Brain Atrophy: The SMART-MR Study
Apr 2023 in Cerebrovascular diseases (Basel, Switzerland) 52 (2), p. 226-233 -
Strategic infarct locations for post-stroke depressive symptoms: a lesion- and disconnection-symptom mapping study
Apr 2023 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 8 (4), p. 387-396 -
White Matter Hyperintensity Volume and Poststroke Cognition: An Individual Patient Data Pooled Analysis of 9 Ischemic Stroke Cohort Studies
Dec 2023 in Stroke 54 (12), p. 3021-3029 -
Geometric Deep Learning using Vascular Surface Meshes for Modality-Independent Unruptured Intracranial Aneurysm Detection
Nov 2023 in IEEE transactions on medical imaging 42 (11), p. 3451-3460 -
Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts
2023 in NeuroImage. Clinical 40 p. 103547 -
Implications of quantitative susceptibility mapping at 7 Tesla MRI for microbleeds detection in cerebral small vessel disease
2023 in Frontiers in Neurology 14 -
Multimodal tract-based MRI metrics outperform whole brain markers in determining cognitive impact of small vessel disease-related brain injury
Sep 2022 in Brain structure & function 227 (7), p. 2553-2567 -
Explainable artificial intelligence (XAI) in deep learning-based medical image analysis
Jul 2022 in Medical Image Analysis 79 p. 1-21 -
Microinfarcts in the Deep Gray Matter on 7T MRI: Risk Factors, MRI Correlates, and Relation to Cognitive Functioning-The SMART-MR Study
Jun 2022 in AJNR. American journal of neuroradiology 43 (6), p. 829-836 -
Automatic quantification of perivascular spaces in T2-weighted images at 7 T MRI
Apr 2022 in Cerebral Circulation - Cognition and Behavior 3 p. 1-9 -
Blood Flow Velocity Pulsatility and Arterial Diameter Pulsatility Measurements of the Intracranial Arteries Using 4D PC-MRI
Apr 2022 in Neuroinformatics 20 (2), p. 317-326 -
Quantification of Calcium in Peripheral Arteries of the Lower Extremities: Comparison of Different CT Scanners and Scoring Platforms
Mar 2022 in Investigative Radiology 57 (3), p. 141-147 -
Association of Early MRI Characteristics With Subsequent Epilepsy and Neurodevelopmental Outcomes in Children With Tuberous Sclerosis Complex
Mar 2022 in Neurology 98 (12), p. e1216-e1225 -
Relationship between 3D Morphologic Change and 2D and 3D Growth of Unruptured Intracranial Aneurysms
Mar 2022 in American Journal of Neuroradiology 43 (3), p. 416-421 -
Association Between Cerebral Cortical Microinfarcts and Perilesional Cortical Atrophy on 3T MRI
Feb 2022 in Neurology 98 (6), p. E612-E622 -
White matter hyperintensity shape is associated with cognitive functioning - the SMART-MR study
Dec 2022 in Neurobiology of Aging 120 p. 81-87 -
Brain Deep Medullary Veins on 7T MRI in Dutch-Type Hereditary Cerebral Amyloid Angiopathy
Oct 2022 in Journal of Alzheimer's disease : JAD 90 (1), p. 381-388 -
Computed tomography-based calcium scoring in cadaver leg arteries: Influence of dose, reader, and reconstruction algorithm
Jan 2022 in European Journal of Radiology 146 -
Network impact score is an independent predictor of post-stroke cognitive impairment: A multicenter cohort study in 2341 patients with acute ischemic stroke
2022 in NeuroImage. Clinical 34 p. 1-7 -
Reliability and Agreement of 2D and 3D Measurements on MRAs for Growth Assessment of Unruptured Intracranial Aneurysms
Sep 2021 in American Journal of Neuroradiology 42 (9), p. 1598-1603 -
Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts
Jun 2021 in Lancet Neurology 20 (6), p. 448-459 -
Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease-The SMART-MR study
Jun 2021 in Journal of Cerebral Blood Flow and Metabolism 41 (6), p. 1219-1228 -
Detection of Cerebral Microbleeds With Venous Connection at 7 Tesla MRI
Apr 2021 in Neurology 96 (16), p. e2048-e2057 -
The Impact of Strategic White Matter Hyperintensity Lesion Location on Language
Feb 2021 in The American Journal of Geriatric Psychiatry 29 (2), p. 156-165 -
Bringing AI to the clinic: blueprint for a vendor-neutral AI deployment infrastructure
Dec 2021 in Insights Into Imaging [E] 12 (1), p. 11 -
An anomaly detection approach to identify chronic brain infarcts on MRI
Dec 2021 in Scientific Reports 11 (1), -
Cortical cerebral microinfarcts on 7T MRI: Risk factors, neuroimaging correlates and cognitive functioning - The Medea-7T study
Nov 2021 in Journal of Cerebral Blood Flow and Metabolism 41 (11), p. 3127-3138 -
Anatomy of phonemic and semantic fluency: A lesion and disconnectome study in 1231 stroke patients
Oct 2021 in Cortex 143 p. 148-163 -
Post-stroke cognitive impairment on the Mini-Mental State Examination primarily relates to left middle cerebral artery infarcts
Oct 2021 in International Journal of Stroke 16 (8), p. 981-989 -
Arterial Remodeling of the Intracranial Arteries in Patients With Hypertension and Controls: A Postmortem Study
Jan 2021 in Hypertension (Dallas, Tex. : 1979) 77 (1), p. 135-146 -
Subvoxel vessel wall thickness measurements of the intracranial arteries using a convolutional neural network
Jan 2021 in Medical Image Analysis 67 p. 1-10 -
Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs” study
Jan 2021 in Cerebral Circulation - Cognition and Behavior 2 -
Generative lesion pattern decomposition of cognitive impairment after stroke
2021 in Brain communications 3 (2), -
The Effects of Intracranial Stenosis on Cerebral Perfusion and Cognitive Performance
2021 in Journal of Alzheimer's Disease 79 (3), p. 1369-1380 -
Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion
Sep 2020 in Journal of Cerebral Blood Flow and Metabolism 40 (9), p. 1869-1878 -
TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study
Sep 2020 in Genetics in medicine : official journal of the American College of Medical Genetics 22 (9), p. 1489-1497 -
High white matter hyperintensity burden in strategic white matter tracts relates to worse global cognitive performance in community-dwelling individuals
Jul 2020 in Journal of the Neurological Sciences 414 p. 1-6 -
Contrast leakage distant from the hematoma in patients with spontaneous ICH: A 7 T MRI study
May 2020 in Journal of Cerebral Blood Flow and Metabolism 40 (5), p. 1002-1011 -
Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease
May 2020 in JAMA Neurology 77 (5), p. 643-647 -
Perinatal thalamic injury: MRI predictors of electrical status epilepticus in sleep and long-term neurodevelopment
Apr 2020 in NeuroImage. Clinical 26 -
Microbleeds colocalize with enlarged juxtacortical perivascular spaces in amnestic mild cognitive impairment and early Alzheimer's disease: A 7 Tesla MRI study
Apr 2020 in Journal of Cerebral Blood Flow and Metabolism 40 (4), p. 739-746 -
Patient-specific fine-tuning of convolutional neural networks for follow-up lesion quantification
Nov 2020 in Journal of Medical Imaging 7 (6), p. 1-15 -
ExploreASL: An image processing pipeline for multi-center ASL perfusion MRI studies
Oct 2020 in NeuroImage 219 -
Small vessel disease lesion type and brain atrophy: The role of co-occurring amyloid
2020 in Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 12 (1), p. 1-11 -
Vascular Risk Factors of Hippocampal Subfield Volumes in Persons without Dementia: The Medea 7T Study
2020 in Journal of Alzheimer's Disease 77 (3), p. 1223-1239 -
Influence of Comorbidity of Cerebrovascular Disease and Amyloid-beta on Alzheimer's Disease
2020 in Journal of Alzheimer's Disease 73 (3), p. 897-907 -
Sex differences in memory clinic patients with possible vascular cognitive impairment
2020 in Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 12 (1), p. 1-10 -
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Sep 2019 in Jove-Journal of visualized experiments 2019 (151), -
Impact of white matter hyperintensity location on depressive symptoms in memory-clinic patients: a lesion–symptom mapping study
Jul 2019 in Journal of Psychiatry and Neuroscience 44 (4), p. E1-E10 -
Cortical Microinfarcts and White Matter Connectivity in Memory Clinic Patients
Jun 2019 in Frontiers in Neurology 10 (JUN), p. 571 -
Automatic classification of focal liver lesions based on MRI and risk factors
May 2019 in PLoS ONE 14 (5), -
Quantifying cardiac-induced brain tissue expansion using DENSE
Feb 2019 in NMR in Biomedicine 32 (2), p. e4050 -
Volumetric assessment of extracranial carotid artery aneurysms
Dec 2019 in Scientific Reports 9 (1), -
Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions
Dec 2019 in Neurobiology of Aging 84 p. 225-234 -
The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study
Dec 2019 in Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 11 (1), p. 310-326 -
The association between lacunes and white matter hyperintensity features on MRI: The SMART-MR study
Dec 2019 in Journal of Cerebral Blood Flow and Metabolism 39 (12), p. 2486-2496 -
Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset
Nov 2019 in Scientific Reports 9 (1), -
Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge
Nov 2019 in IEEE Transactions on Medical Imaging 38 (11), p. 2556-2568 -
Intracranial Vessel Wall Magnetic Resonance Imaging Does Not Allow for Accurate and Precise Wall Thickness Measurements: An Ex Vivo Study
Oct 2019 in Stroke 50 (10), p. e283-e284 -
The contribution of acute infarcts to cerebral small vessel disease progression
Oct 2019 in Annals of Neurology 86 (4), p. 582-592 -
Liver segmentation and metastases detection in MR images using convolutional neural networks
Oct 2019 in Journal of Medical Imaging 6 (4), -
The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus
Jan 2019 in Journal of Alzheimer's Disease 68 (1), p. 311-322 -
Data on vessel wall thickness measurements of intracranial arteries derived from human circle of Willis specimens
Aug 2018 in Data in Brief 19 p. 6-12 -
Strategic infarct location for post-stroke cognitive impairment: A multivariate lesion-symptom mapping study
Aug 2018 in Journal of Cerebral Blood Flow and Metabolism 38 (8), p. 1299-1311 -
Body representation disorders predict left right orientation impairments after stroke: A voxel-based lesion symptom mapping study
Jul 2018 in Cortex 104 (july), p. 140-153 -
Ex vivo vessel wall thickness measurements of the human circle of Willis using 7T MRI
Jun 2018 in Atherosclerosis 273 p. 106-114 -
Automated Multi-Atlas Segmentation of Hippocampal and Extrahippocampal Subregions in Alzheimer's Disease at 3T and 7T: What Atlas Composition Works Best?
Apr 2018 in Journal of Alzheimer's Disease 63 (1), p. 217-225 -
Impact of different palliative systemic treatments on skeletal muscle mass in metastatic colorectal cancer patients
Oct 2018 in Journal of Cachexia, Sarcopenia and Muscle 9 (5), p. 909-919 -
White matter hyperintensity shape and location feature analysis on brain MRI; Proof of principle study in patients with diabetes
Jan 2018 in Scientific Reports 8 (1), p. 1-10 -
Brain imaging correlates of mild cognitive impairment and early dementia in patients with type 2 diabetes mellitus
2018 in Nutrition, Metabolism and Cardiovascular Diseases 28 (12), p. 1253-1260 -
Evaluation of a deep learning approach for the segmentation of brain tissues and white matter hyperintensities of presumed vascular origin in MRI
2018 in Neuroimage: Clinical [E] 17 p. 251-262 -
Evaluation of motion correction for clinical dynamic contrast enhanced MRI of the liver
Sep 2017 in Physics in Medicine and Biology 62 (19), p. 7556-7568 -
High-resolution intracranial vessel wall MRI in an elderly asymptomatic population: comparison of 3T and 7T
Apr 2017 in European Radiology 27 (4), p. 1585–1595 -
Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy
Mar 2017 in Acta Neuropathologica 133 (3), p. 409-415 -
Evolution of cerebral microbleeds after cranial irradiation in medulloblastoma patients
Feb 2017 in Neurology 88 (8), p. 789-796 -
Corrigendum to “The right hemisphere is dominant in organization of visual search—A study in stroke patients” [Behav. Brain Res. 304 (2016) 71–79]((S0166432816300626)(10.1016/j.bbr.2016.02.004))
Feb 2017 in Behavioural Brain Research 319 p. 234 -
Morphological characteristics of diffuse idiopathic skeletal hyperostosis in the cervical spine
Nov 2017 in PLoS ONE [E] 12 (11), p. 1-11 -
Visuospatial Functioning in Cerebral Amyloid Angiopathy: A Pilot Study
2017 in Journal of Alzheimer's Disease 56 (4), p. 1223-1227 -
Abnormalities of Cerebral Deep Medullary Veins on 7 Tesla MRI in Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease: A Pilot Study
2017 in Journal of Alzheimer's Disease 57 (3), p. 705-710 -
Assessment of blood flow velocity and pulsatility in cerebral perforating arteries with 7-T quantitative flow MRI
Sep 2016 in NMR in Biomedicine 29 (9), p. 1295-1304 -
Strong evidence for pattern separation in human dentate gyrus
Jul 2016 in Journal of Neuroscience 36 (29), p. 7569-7579 -
Automated hippocampal subfield segmentation at 7T MRI
Jun 2016 in American Journal of Neuroradiology 37 (6), p. 1050-1057 -
The right hemisphere is dominant in organization of visual search-A study in stroke patients
May 2016 in Behavioural Brain Research 304 p. 71-79 -
Impact of Strategically Located White Matter Hyperintensities on Cognition in Memory Clinic Patients with Small Vessel Disease
Nov 2016 in PLoS ONE [E] 11 (11), -
Quantification of deep medullary veins at 7 T brain MRI
Oct 2016 in European Radiology 26 (10), p. 3412-3418 -
Erratum to "Subfields of the hippocampal formation at 7T MRI: In vivo volumetric assessment" [NeuroImage 61 (2012) 1043-1049]
Jan 2016 in NeuroImage 125 p. 1176-1177 -
Cortical microinfarcts on 3T MRI: Clinical correlates in memory-clinic patients
Dec 2015 in Alzheimer's & Dementia 11 (12), p. 1500-1509 -
Distinct anatomical correlates of discriminability and criterion setting in verbal recognition memory revealed by lesion-symptom mapping
Jan 2015 in Human Brain Mapping 36 (4), p. 1292-1303 -
Microstructural brain abnormalities in Huntington's disease: A two-year follow-up
Jan 2015 in Human Brain Mapping 36 (6), p. 2061-2074 -
Hippocampal Disconnection in Early Alzheimer's Disease: A 7 Tesla MRI Study
2015 in Journal of Alzheimer's Disease 45 (4), p. 1247-1256 -
MRBrainS Challenge: Online Evaluation Framework for Brain Image Segmentation in 3T MRI Scans
2015 in Computational Intelligence and Neuroscience 2015 -
Automatic extraction of the midsagittal surface from brain MR images using the kullback-leibler measure
2014 in Neuroinformatics 12 (3), p. 395-403 -
Visualization of the aneurysm wall: a 7.0-tesla magnetic resonance imaging study
2014 in Neurosurgery 75 (6), p. 614-622 -
The anatomy of visuospatial construction revealed by lesion-symptom mapping
2014 in Neuropsychologia 62 (1), p. 68-76 -
Cerebral microvascular lesions on high-resolution 7-tesla MRI in patients with type 2 diabetes
2014 in Diabetes 63 (10), p. 3523-3529 -
Cerebral cortical microinfarcts at 7Tesla MRI in patients with early Alzheimer's disease
2014 in Journal of Alzheimer's Disease 39 (1), p. 163-167 -
Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging
2014 in Neurobiology of Aging 35 (9), p. 2039-2045 -
Tracking of cell nuclei for assessment of in vitro uptake kinetics in ultrasound-mediated drug delivery using fibered confocal fluorescence microscopy
2014 in Molecular Imaging and Biology 16 (5), p. 642-651 -
Visualization of perivascular spaces and perforating arteries with 7 T magnetic resonance imaging
2014 in Investigative Radiology 49 (5), p. 307-313 -
How to assess the reliability of cerebral microbleed rating?
2013 in Frontiers in Aging Neuroscience [E] 5 p. 57 -
Quantitative analysis of the closure pattern of the neurocentral junction as related to preexistent rotation in the normal immature spine.
2013 in The Spine Journal 13 (7), p. 756-763 -
Semi-automated detection of cerebral microbleeds on 3.0 T MR images
2013 in PLoS ONE [E] 8 (6), p. e66610 -
Association between Subcortical Vascular Lesion Location and Cognition: A Voxel-Based and Tract-Based Lesion-Symptom Mapping Study. The SMART-MR Study
2013 in PLoS ONE [E] 8 (4), p. e60541 -
Subfields of the hippocampal formation at 7T MRI: In vivo volumetric assessment
Jul 2012 in NeuroImage 61 (4), p. 1043-1049 -
Subfields of the hippocampal formation at 7 T MRI: in vivo volumetric assessment.
2012 in NeuroImage 61 (4), p. 1043-1049 -
Efficient detection of cerebral microbleeds on 7.0T MR images using the radial symmetry transform
2012 in NeuroImage 59 (3), p. 2266-2273